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Chronic Pain

Below is a sample of existing clinical evidence:

“A single systemic injection of hMSCs (human Mesenchymal Stem Cells) into the tail vein was able to reduce NP-like behaviors and to modify molecular and cellular pain-associated pathways… hMSCs were able to reduce pain-like behaviors, such as mechanical allodynia and thermal hyperalgesia, once injected into the tail vein. An anti-nociceptive effect was detectable from day 11 post surgery (7 days post cell injection). hMSCs were mainly able to home in the spinal cord and pre-frontal cortex of neuropathic mice.”

– “Long lasting effects of hMSC systemic administration on pain-like behaviors, cellular & biomolecular modificaiton in neuropathic mice,” Siniscalco et al, Frontiers in Integrative Neuroscience, 2011

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